Will Keepod affect my computer in any way after I’m finished using it?

No. The Keepod system does not interfere at all with the computer. It does not impact any existing hard drives or locally installed systems. After you unplug your Keepod, it is as if you were never there. If the computer is used again without the Keepod, it will start with its original operating system, whether the Keepod was used one time with the computer or set to a permanent boot.